The manual in my Marine Power 454 mag recommends strait 40W oil. I used that for about 100 hours. Then I switched to Syn Oil (specifically Mobil 1). The heaviest they offer is 15W50 hence what I use. I have also used Valvoline full Syn in 20W-50 and it works good also.
The things I notice about Syn versus conventional oil is the oil pressure stays higher when hot. To me that says the oil is generally running cooler or not thinning as much with heat.