Fuel injection will give you better cold start and economy, but I've always been partial to the simplicity of the carb. I'm know I sound like a dinosuar, but if something goes south, you can check if you're getting fuel and spark and with a little creativity (and some jumpers) a lot of times you can jury rig the carb set-up if it peters out on you 50 miles up the lake! If you only want 400-450 horsepower, it shouldn't be a real bear around the dock either since you wouldn't need a big rumpity rump cam! Just my antiquated opinion.
Craig