To properly trim for spped, you must watch your sppedo and tach in unison. Top rpm, doesn't equate to top speed. If you over trim, rpm will go up, but your speed will go down. What you need to do, is to trim up while watching your speedo, and when you reach your maximum speed, look at where your tach is. This will let you know if you are propped right. You should be up near the rev limiter, but not bumping it. If you are hitting the rev limiter, add more pitch, and conversely, if you are down on rpm's, reduce the pitch.
This being said, all this only holds true to the conditions you are running in at that moment. Cool air vs. hot air, dense air vs. thin air, load of boat, surface conditions, elevation etc., make it beneficial to have more then one prop.