Mopar has always been somewhat of an underdog, but when it comes to steppiing up to the plate, they've always held their own. There are some very state of the art performance parts available, and I don't see why you couldn't build as nice a Mopar motor as anything else out there. You'll just have to spend a little more, and do a lot more homework to find out what's out there that works, and what guys are running. I think it's a great idea.
Go for it!